Boc-D-glutamic acid 5-benzyl ester

Boc-D-glutamic acid 5-benzyl ester - Names and Identifiers

Name	Boc-D-Glu(OBzl)-OH
Synonyms	BOC-GLU(OBZL)-OH BOC-L-GLU(BZL)-OH Boc-D-Glu(OBzl)-OH BOC-L-GLU(OBZL)-OH BOC-GLUTAMIC ACID(OBZL)-OH BOC-L-GLUTAMIC ACID (OBZL) Boc-L-Glutamic Acid-5-Benzyl Ester BOC-L-GLUTAMIC ACID G-BENZYL ESTER Boc-D-Glutamic acid 5-benzyl ester Boc-D-glutamic acid 5-benzyl ester BOC-L-GLUTAMIC ACID GAMMA-BENZYL ESTER T-BUTYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-BENZYL ESTER (2R)-5-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name)
CAS	35793-73-8
EINECS	237-007-5
InChI	InChI=1/C17H23NO6/c1-17(2,3)24-16(22)18-13(15(20)21)9-10-14(19)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,20,21)/t13-/m1/s1

Boc-D-glutamic acid 5-benzyl ester - Physico-chemical Properties

Molecular Formula	C17H23NO6
Molar Mass	337.37
Density	1?+-.0.06 g/cm3(Predicted)
Melting Point	69-71°C
Boling Point	522.6±50.0 °C(Predicted)
Specific Rotation(α)	5.5 º (c=1% in acetic acid)
Flash Point	269.9°C
Vapor Presure	9.49E-12mmHg at 25°C
pKa	3.81±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.523

Boc-D-glutamic acid 5-benzyl ester - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

Boc-D-glutamic acid 5-benzyl ester - Introduction

Boc-D-Glu(OBzl)-OH(Boc-D-Glu(OBzl)-OH) is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystalline powder
-Molecular formula: C20H25NO6
-Molecular Weight: 379.41
-melting point: 118-120 ℃
-Solubility: Soluble in some organic solvents, such as methanol and dichloromethane

Use:
- Boc-D-Glu(OBzl)-OH is commonly used in the field of drug synthesis and peptide synthesis.
-It can be used as a protecting group for peptides to protect the hydroxyl functional group of glutamic acid during the synthesis process to prevent undesirable reactions during the reaction.

Preparation Method:
- Boc-D-Glu(OBzl)-OH is usually prepared by chemical synthesis.
-First, tert-butoxycarbonyl (Boc) is introduced into the glutamic acid molecule to produce tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-Then, a benzyl group (Bzl) is introduced into the hydroxyl group of glutamic acid to form Boc-D-Glu(OBzl)-OH(Boc-D-Glu(OBzl)-OH).

Safety Information:
- Boc-D-Glu(OBzl)-OH is an organic compound, which may cause certain irritation and harm to the human body.
-During use, pay attention to avoid contact with skin, eyes and respiratory tract.
-In laboratory operations or industrial production, appropriate personal protective equipment should be used, such as gloves, protective glasses and protective masks.
-Store away from fire and oxidizing agents, keep the container sealed, and store in a cool and dry place.

Please note that this is general information only and does not relate to specific experimental conditions and safe practices. Before using this compound, it is recommended to consult the detailed chemical substance safety data sheet (MSDS) and follow the relevant safety practices.

Last Update：2024-04-09 21:01:54